The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 1995
Filed:
Jun. 18, 1992
Paul D Olivo, St. Louis, MO (US);
Washington University, St. Louis, MO (US);
Abstract
A diagnostic assay for detecting the presence of an infectious herpes virus in a specimen and a genetically engineered cell line for use in such assay are disclosed. The cell line used in the assay expresses a reporter gene only if infectious herpes virus is present in the specimen. The assay involves inoculating a DNA-transfected cell line with a specimen suspected of containing a herpes virus, allowing a sufficient period of time for the herpes virus infectious cycle to proceed, and detecting and quantifying the number of herpes virus-infected cells to determine the number of infectious herpes virus virions in the specimen. The cell line is a DNA-transfected cell line susceptible to infection by a herpes virus which is stably transformed with a chimeric gene comprising a herpes virus inducible promoter and a gene coding for an enzyme, the expression of the enzyme being dependent upon and quantitatively proportional to the presence of herpes virus. A kit for such assay is also provided.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile