The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 1995
Filed:
Jan. 13, 1994
Thomas R Covey, Richmond Hill, CA;
Joseph F Anacleto, Brampton, CA;
MDS Health Group Limited, Etobicoke, CA;
Abstract
Liquid from a liquid chromatograph or other sample source, preferably assisted by a high velocity coaxial gas jet, is sprayed through a capillary tube producing a flow in a first direction of charged droplets. A flow of heated gas, in a second direction different from the first direction, intersects the droplet flow at a region upstream of an orifice. The flows mix turbulently, with the second flow helping to evaporate the droplets to produce ions and helping to move the evaporating droplets toward the orifice, providing a focusing effect. Ions are drawn through the orifice into a mass analyzer and analyzed. Alternatively the flows of liquid and heating gas can be directed toward each other and at right angles to the axis through the orifice, and the inhaling effect of the orifice can be used to draw droplets toward it, or a third gas flow can be used for this purpose. The heated intersecting gas flow typically provides an increase in sensitivity (ion counts per second) of between 10 and 100 times. Heating the droplet plume also allows controlled desaturation of ions and in increase in the number of charges on them, without degrading the ions.