The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 1995

Filed:

Feb. 18, 1993
Applicant:
Inventors:

Ingegerd Hellstrom, Seattle, WA (US);

Karl E Hellstrom, Seattle, WA (US);

Hans Marquardt, Mercer Island, WA (US);

Janet Johnston, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07K / ;
U.S. Cl.
CPC ...
43524027 ; 53038815 ; 5303883 ; 5303873 ; 5303913 ; 5303879 ; 4351722 ; 435 7021 ;
Abstract

The present invention is concerned with novel monoclonal antibody L53 which binds strongly to a glycoprotein antigen associated with human tumors, including carcinomas of the colon, breast, and lung, as well as melanomas. The antibody binds to normal human cells to a much lesser degree than to tumor cells. The antibody finds use in diagnostic methods for as the detection of malignant cells associated with tumors. Also disclosed is a novel 70,000-75,000 dalton glycoprotein antigen recognized by MAb L53. The L53 antigen is found on the cell surface of human tumor cells. The amino terminal amino acid sequence of this antigen is: ##STR1## in which X represents an unidentified amino acid.


Find Patent Forward Citations

Hellstrom, Ingegerd. (1995). Monoclonal antibody l53 which recognizes a human tumor-associated antigen (U.S. Patent No. 5411884). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5411884

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…