The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 1995

Filed:

Jul. 20, 1993
Applicant:
Inventors:

Dmitri Kirpotin, Denver, CO (US);

Daniel C Chan, Denver, CO (US);

Paul A Bunn, Jr, Evergreen, CO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B / ; A61K / ;
U.S. Cl.
CPC ...
424322 ; 428403 ; 423633 ; 423634 ; 436173 ; 436806 ; 1286534 ; 514-6 ; 514 54 ; 514 59 ; 424647 ;
Abstract

Superparamagnetic particles are provided for medical applications including hyperthermia techniques, localized heating and tissue-specific release of therapeutic agents, and magnetic resonance imaging contrast enhancement, comprising superparamagnetic iron oxide and a polymer such as dextran at a ratio of about 0.5 to 0.1 w/w of polymer to iron. The particles display at least one of the following magnetic properties: (a) specific power absorption rate greater than 300 w/g Fe; (b) initial magnetic susceptibility greater than 0.7 EMU/g Fe/Gauss; and (c) magnetic moment greater than 10.sup.-15 erg/Gauss.


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