The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 1995

Filed:

Sep. 08, 1993
Applicant:
Inventors:

David S Garvey, Lake Forest, IL (US);

George M Carrera, Jr, Des Plaines, IL (US);

Stephen P Arneric, Lindenhurst, IL (US);

Youe-Kong Shue, Sudbury, MA (US);

Nan-Horng Lin, Mundelein, IL (US);

Yun He, Milwaukee, WI (US);

Edmund L Lee, Lake Zurich, IL (US);

Suzanne A Lebold, Chicago, IL (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
514372 ; 514378 ; 514406 ; 548206 ; 548214 ; 548240 ; 548247 ; 5483641 ;
Abstract

Novel isoxazole isothiazole and pyrazole compounds of the formula: ##STR1## wherein A, R.sup.1, and R.sup.2 are specifically defined, or pharmaceutical salts thereof, are selective and potent cholinergic ligands at neuronal nicotinic receptors, useful in the treatment of cognitive, neurological and mental disorders characterized by decreased cholinergic function, as well as in the treatment of alcohol intoxication and petit real absence epilepsy.


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