The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 1995
Filed:
Dec. 13, 1993
Applicant:
Inventors:
Raymond Baker, Much Hadham, GB;
Angus M MacLeod, Bishop's Stortford, GB;
John Saunders, Bishop's Stortford, GB;
Kevin Merchant, Bishop's Stortford, GB;
Assignee:
Merck Sharpe & Dohme Ltd., Hoddesdon, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514299 ; 514305 ; 514312 ; 514361 ; 546112 ; 546133 ; 546277 ; 548128 ;
Abstract
A class of novel thiadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring system, and substituted on the other ring carbon atom with a substituent of low lipophilicity, or a hydrocarbon substituent; are potent muscarinic agonists, and have good CNS penetrability. The compounds are therefore useful in the treatment of neurological and mental illnesses, and are also of benefit in the treatment of severe painful conditions.