The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 1995

Filed:

Apr. 08, 1991
Applicant:
Inventors:

James A Braatz, Beltsville, MD (US);

Aaron H Heifetz, Columbia, MD (US);

Assignee:

W. R. Grace & Co.-Conn., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436531 ; 528 48 ; 528 52 ; 528 53 ; 528 59 ; 528904 ; 427-213 ; 4272071 ; 427221 ; 427435 ; 21050024 ; 4284231 ; 4284239 ; 4284242 ; 4284246 ; 4284251 ; 4284255 ; 4284256 ; 604-8 ; 604 19 ; 604403 ; 435174 ; 435176 ; 435181 ; 435182 ; 525403 ; 525418 ; 525420 ; 525424 ; 525454 ; 436120 ; 436129 ; 436131 ;
Abstract

Affinity matrices useful for the chromatography and immobilization of biological materials and the method of preparing and using the same are disclosed. The affinity supports are based on hydrated polyurethane polymers which have been activated to provide a means for covalently attaching a variety of bioaffinity agents. The hydrated polymer matrices are characterized by their biocompatibility and resistance to nonspecific protein adsorption. Preferably, the prepolymers used to prepare the hydrated polymers are isocyanate-capped oxyethylene-based diols or polyols, at least 75% of said diols and polyols having a molecular weight of 7000 to about 30,000.


Find Patent Forward Citations

Braatz, James. (1995). Biocompatible, low protein adsorption affinity matrix (U.S. Patent No. 5403750). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5403750

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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