The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 1995
Filed:
Apr. 20, 1994
Applicant:
Inventors:
Michael A Poss, Lawrenceville, NJ (US);
Paul D Pansegrau, E. Windsor, NJ (US);
Shaopeng Wang, E. Windsor, NJ (US);
John K Thottathil, Robbinsville, NJ (US);
Janak Singh, Lawrenceville, NJ (US);
Richard H Mueller, Ringoes, NJ (US);
Assignee:
Bristol-Myers Squibb Co., Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ;
U.S. Cl.
CPC ...
549448 ;
Abstract
A method is provided for preparing carboxylic acid intermediates of the structure ##STR1## wherein an aldehyde of the structure ##STR2## is prepared and subjected to a Horner-Emmons reaction to form the ester of the structure ##STR3## and the ester is hydrogenated to the carboxylic acid which may be used in making the final anti-thrombotic--anti-vasospastic compounds.