The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 1995
Filed:
Nov. 02, 1990
Maria Gazdag, Budapest, HU;
Gabor Szepesi, Budapest, HU;
Takacsi Nagy, Budapest, HU;
Szikla Z Papp, Budapest, HU;
Laszlo Nagy, Budapest, HU;
Eva E Kiss, Budapest, HU;
Bobjak M Zsoldos, Budapest, HU;
Richter Gedeon Vegyeszeti Gyar Rt., Budapest, HU;
Abstract
The invention relates to novel, parenterally useful, stable aqueous pharmaceutical compositions, mainly injectable solutions containing a bis-indole alkaloid. The compositions contain the zinc complex of a bis-indole alkaloid, preferably vincristine, vinblastine or 5'-nor-dihydrovinblastine together with a bivalent metal gluconate and a preserving agent dissolved in a mono- or polyhydric alcohol. The invention further relates to a process for the preparation of the above compositions. The composition according to the invention can be utilized for the parenteral administration of bis-indole alkaloids in the cancer chemotherapy.