The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 1995
Filed:
Jun. 04, 1993
Applicant:
Inventors:
Rafael Foguet, Barcelona, ES;
Jordi Bolos, Barcelona, ES;
Aurelio Sacristan, Barcelona, ES;
Jose A Ortiz, Barcelona, ES;
Assignee:
Ferrer Internacional, S.A., Barcelona, ES;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514317 ; 546 16 ; 546236 ; 546237 ;
Abstract
4-Benzylpiperidine derivatives of the formula: ##STR1## or a pharmaceutically acceptable acid addition salt thereof, wherein X is hydrogen or fluorine and R is hydrogen, or a group selected from p-fluorobenzoyl, .alpha.-hydroxy-p-fluorobenzyl, p-fluorophenoxy, bis(p-fluorophenyl)methyl and 8-azaspiro[4,5]decane-7,9-dione-8-yl-methyl, with the proviso that X and R may not be simultaneously hydrogen and p-fluorobenzoyl respectively. Such compounds are useful as sigma-receptor ligands.