The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 1995
Filed:
Aug. 20, 1993
Applicant:
Inventors:
Bernard Knapp, Marburg-Schrock, DE;
Erika Hundt, Marburg-Wehrshausen, DE;
Burkhard Enders, Marburg, DE;
Hans Kupper, Marburg, DE;
Assignee:
Behringwerke Aktiengesellschaft, Marburg/Lahn, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
4241911 ; 514-2 ; 514 12 ; 435 693 ; 530324 ; 530350 ; 530395 ; 530855 ; 4242681 ;
Abstract
Recombinant histidine-rich protein of Plasmodium falciparum, its preparation and use. It was possible, by screening two different Plasmodium falciparum cDNA gene banks with an antiserum against a 41 kD protein and by cross-hybridization with the insert DNA of a clone obtained therewith, to isolate a gene which codes for a Histidine-Alanine-rich protein (HRP-II). This protein protects aotus monkeys from infection with P. falciparum and is thus a suitable constituent of a malaria vaccine.