The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 1995

Filed:

Feb. 08, 1993
Applicant:
Inventors:

Armin Heckel, Biberach, DE;

Robert Sauter, Laupheim, DE;

Manfred Psiorz, Ingelheim am Rhein, DE;

Klaus Binder, Warthausen, DE;

Thomas Mueller, Biberach, DE;

Rainer Zimmermann, Mittelbiberach, DE;

Assignee:

Karl Thomae GmbH, Biberach an der Riss, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514322 ; 514338 ; 546199 ; 546271 ;
Abstract

The invention relates to benzimidazolyl derivatives of general formula ##STR1## wherein R.sub.1 to R.sub.3 are defined as in claim 1, the mixtures of position isomers thereof and the salts thereof, which have valuable pharmacological properties, particularly the effect of extending the thrombin time, a thrombin inhibiting effect and an inhibiting effect on related serine proteases such as trypsin, pharmaceutical compositions containing this compound and processes for the preparation thereof.


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