The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 1995
Filed:
Feb. 04, 1993
Applicant:
Inventors:
Jean-Louis Peglion, le Vesinet, FR;
Ghanem Aasssi, Saint Cloud, FR;
Alain Pierre, Marly le Roi, FR;
Laurence Kraus-Berthier, Colombes, FR;
Nicolas Guilbaud, Paris, FR;
Jean-Paul Vilaine, Chatenay Malabry, FR;
Assignee:
Adir et Compagnie, Courbevoie, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514307 ; 514314 ; 514321 ; 514332 ; 514336 ; 514338 ; 514339 ; 514356 ; 546147 ; 546174 ; 546263 ; 546270 ; 546271 ; 546273 ; 546284 ; 546321 ;
Abstract
The compounds are 2,4-disubstituted 3-ethoxycarbonyl 5-methoxycarbonyl 6-methyl 1,4-dihydropyridines in their dextrorotatory form, useful to potentiate the activity of cytotoxic agents and to increase the sensitivity of tumor cells to antitumor agents. A compound disclosed is d-2-{[2-(2-(N-p-nitrobenzylamino)ethoxy)ethoxy]methyl}-4-(2,3-dichlorophen yl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine.