The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 1995
Filed:
Jan. 05, 1993
Applicant:
Inventors:
Noubar B Afeyan, Brookline, MA (US);
Hossein K Hodjat, Jamaica Plain, MA (US);
Laszlo Varady, Malden, MA (US);
Assignee:
PerSeptive Biosystems, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D / ; B05D / ; C08F / ; C08F / ;
U.S. Cl.
CPC ...
428523 ; 2101982 ; 21050034 ; 21050038 ; 21050041 ; 2105021 ; 210635 ; 210656 ; 428403 ; 428407 ; 428521 ; 502402 ; 521 31 ; 521 32 ; 521 33 ;
Abstract
A method of derivatizing a chromatography matrix having a hydrophobic surface involves reacting the hydrophobic surface with a halosulfonating agent to produce a significant amount of halosulfone groups covalently bonded onto the surface. Sulfonamide bonds then are formed between these halosulfone groups and a group of amine functions on a polyaminated polymer to produce a pellicular anion exchange layer covalently bonded to the surface. The resulting layer is stable in the absence of cross-links between the molecules of the polyaminated polymer.