The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 1995

Filed:

Nov. 04, 1993
Applicant:
Inventors:

Van Au, Congers, NY (US);

Bijan Harichian, South Orange, NJ (US);

Michael I Hill, Ridgewood, NJ (US);

Mikhail Raykh, Brooklyn, NY (US);

Jerry J Krupa, Rockaway Township, Morris County, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07G / ; C07H / ;
U.S. Cl.
CPC ...
536185 ; 536-111 ; 536-41 ; 536 179 ; 536 53 ; 536 221 ; 536124 ;
Abstract

N-substituted aldonamides are synthesized by the reaction of alkylamines and aldonolactone. Commercially available sources of aldonolactones (e.g., lactobiono-1,5-lactone) include aldonic acid (e.g., lactobionic acid). The presence of the acid leads to the formation of an ammonium salt impurity. The ammonium salt formation during the synthesis of N-alkyl aldonamides was minimized by the addition of an external acid. External acids and, optionally, emulsifiers were utilized to substantially reduce or eliminate the formation of an ammonium salt and to obtain N-substituted aldonamides of high purity.


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