The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 1995
Filed:
Mar. 29, 1993
Applicant:
Inventor:
Hiroyuki Kageyama, Shizuoka, JP;
Assignee:
Ihara Chemical Industry Co., Ltd., Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07C / ;
U.S. Cl.
CPC ...
558359 ; 558411 ; 560-8 ;
Abstract
A method for producing an asymmetric biaryl derivative which comprises dehalogenocoupling halogenated benzene derivatives, wherein a bromobenzene derivative of the formula: ##STR1## wherein R is a lower alkyl group or a lower alkoxy group, which is attached at the 3- or 4-position, and a 2-chlorobenzene derivative of the formula: ##STR2## wherein R' is a cyano group or an alkoxycarbonyl group, are reacted in pyridine in the presence of triphenylphosphine, an anhydrous nickel compound and a reducing metal to obtain an asymmetric biaryl derivative of the formula: ##STR3## wherein R and R' are as defined above, and R is attached at the 3- or 4-position.