The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 1995
Filed:
Jul. 30, 1993
Applicant:
Inventors:
Yasuhiro Morisawa, Tokyo, JP;
Mitsuru Kataoka, Tokyo, JP;
Yuichiro Yabe, Tokyo, JP;
Yasuteru Iijima, Tokyo, JP;
Hidekuni Takahagi, Tokyo, JP;
Hiroyuki Koike, Tokyo, JP;
Tatsuo Kokubu, Ehime, JP;
Kunio Hiwada, Ehime, JP;
Assignee:
Sankyo Company, Limited, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
514 18 ; 514 19 ; 530331 ;
Abstract
Oligopeptides of formula (I): ##STR1## where R.sup.1 -R.sup.5 are various organic groups, and A represents a group of formula --NH-- or --(CH.sub.2).sub.n --, in which n represents an integer of from 1 to 3, have renin-inhibitory activity and are particularly suitable for oral administration. They may be prepared by condensing their component amino acids or lower oligopeptides using conventional peptide synthesis reactions.