The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 1994
Filed:
Oct. 09, 1992
Applicant:
Inventors:
Dinos P Santafianos, Maplewood, NJ (US);
Kathleen M Poss, Lawrenceville, NJ (US);
Eric M Gordon, Palo alto, CA (US);
Peggy J McCann, West Trenton, NJ (US);
Assignee:
E. R. Squibb & Sons, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07C / ;
U.S. Cl.
CPC ...
514428 ; 514429 ; 514460 ; 514510 ; 548517 ; 548579 ; 549292 ; 560119 ;
Abstract
Novel nitrogen-substituted mevinic acid derivatives which inhibit the activity of HMG-CoA reductase. Pharmaceutical compositions, and methods of use for the treatment or prevention of hypercholesterolemia, atherosclerosis, hyperlipoproteinaemia and hyperlipidemia are provided, as are novel methods for preparation and intermediate compounds.