The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 1994

Filed:

Jun. 07, 1993
Applicant:
Inventors:

Robert W Henkens, Durham, NC (US);

Junguo Zhao, Chapel Hill, NC (US);

Marek Wojciechowski, Cary, NC (US);

John P O'Daly, Carrboro, NC (US);

Zhi-Wei Liang, Durham, NC (US);

Susan E Morris, Chapel Hill, NC (US);

Assignee:

Andcare, Inc., Durham, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ;
U.S. Cl.
CPC ...
20415312 ; 2041531 ; 204403 ; 436 74 ; 436 77 ;
Abstract

The invention relates to methods of determining micromolar levels of lead ion in various fluids, including blood. Detection of lead or other heavy metal ion concentrations as low as 1 .mu.g/dL is achieved. The methods are adaptable to the detection of low levels of lead in whole blood, employing a novel separation and release of lead ion from lead chelating agents. The disclosed methods employ isocitrate dehydrogenase-based electrodes which are particularly suited for detecting nanomolar levels of lead.


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