The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 1994
Filed:
Jul. 20, 1992
Applicant:
Inventors:
George Chang, Ivoryton, CT (US);
Ernest S Hamanaka, Gales Ferry, CT (US);
Peter A McCarthy, Pawcatuck, CT (US);
Thien Truong, Saybrook, CT (US);
Frederick J Walker, Preston, CT (US);
Assignee:
Pfizer Inc., New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
546296 ; 544317 ; 544326 ; 544327 ; 546143 ; 546159 ; 546309 ; 548152 ; 548178 ; 562512 ; 564 52 ; 564192 ; 564440 ;
Abstract
Compounds of the formula ##STR1## wherein R.sup.21 and R.sup.22 are as defined in the specification which are intermediates useful in the preparation of compounds of the formula ##STR2## and the pharmaceutically acceptable salts thereof, wherein Q and R.sup.1 are as defined in the specification. The compounds of formula I are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.