The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 1994
Filed:
Dec. 01, 1992
Dennis A Moore, Ferguson, MO (US);
Max D Adams, St. Charles, MO (US);
William P Cacheris, Florissant, MO (US);
David H White, Ballwin, MO (US);
Muthunadar P Periasamy, Chesterfield, MO (US);
Raghavan Rajagopalan, Maryland Heights, MO (US);
Lynn A deLearie, University City, MO (US);
Steven R Woulfe, Ballwin, MO (US);
Mallinckrodt Medical, Inc., St. Louis, MO (US);
Abstract
Methods and compositions are disclosed for enhancing .sup.19 F magnetic resonance imaging which utilize .sup.19 F magnetic resonance contrast media having enhanced .sup.19 F relaxivity. Fluorine-containing compounds having enhanced .sup.19 F relaxation properties resulting from direct association with an unpaired spin are disclosed. The fluorine-containing compound is associated with the unpaired spin by covalent attachment of a stable free radical, by complexation of a fluorinated complexing agent with a paramagnetic metal ion, or by salt formation or charge neutralization of a paramagnetic ion.