The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 1994

Filed:

Jun. 29, 1992
Applicant:
Inventors:

Sudershan K Arora, Lansdale, PA (US);

David S Thomson, Bluebell, PA (US);

M Nayeem Akhtar, Lansdale, PA (US);

Assignee:

Greenwich Pharmaceuticals Incorporated, Ft. Washington, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; C07H / ;
U.S. Cl.
CPC ...
514 23 ; 536 173 ; 536 187 ; 536-41 ; 514 25 ;
Abstract

The compounds of this invention are 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom. The saturated nitrogen-containing heterocycle substituent is shown by the following formula: ##STR1## where X is CH.sub.2, NH or O; and n ranges from 3-6. These hexose monosaccharides may also be ethereally substituted at least one other position. The compounds exhibit anti-proliferative and anti-inflammatory activity. Methods of preparation, pharmaceutical compositions containing the compounds and methods of treating inflammatory and/or autoimmune disorders employing the compounds are disclosed.


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