The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 1994
Filed:
Jun. 29, 1992
Tomio Takeuchi, Tokyo, JP;
Takaaki Aoyagi, Fujisawa, JP;
Masa Hamada, Tokyo, JP;
Hiroshi Naganawa, Tokyo, JP;
Keiji Ogawa, Tokyo, JP;
Machiko Nagai, Tokyo, JP;
Yasuhiko Muraoka, Tokyo, JP;
Makoto Tsuda, Tokyo, JP;
Zaidan Hojin Biseibutsu Kagaku Kenkyu KaI, Tokyo, JP;
Abstract
A novel, biologically active substance, poststatin, has been isolated from a culture medium of microorganism belonging to Streptomyces. The novel substance is a peptide compound having a novel structure, wherein the peptide chains have ketone radicals. Thus substance has a high endopeptidase inhibition activity. It is possible to chemically synthesize poststatin related compound having ketone radicals in the peptide chains. These compounds also have an endopeptidase inhibition activity.