The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 1994
Filed:
Feb. 18, 1993
Applicant:
Inventors:
Thomas P Stossel, Belmont, MA (US);
John H Hartwig, Jamaica Plain, MA (US);
Paul A Janmey, Arlington, MA (US);
Assignee:
Brigham and Women's Hospital, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ;
U.S. Cl.
CPC ...
435-2 ; 436-8 ; 514-2 ; 424532 ;
Abstract
Methods for preserving platelets at temperatures of less than about 15.degree.C. with retention of hemostatic activity are provided. The method uses a first agent for inhibiting actin filament severing and a second agent for inhibiting actin polymerization. Contacting the platelets with the first and second agents prior to exposure to cold temperature prevents cold-induced platelet activation.