The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 1994
Filed:
Jun. 09, 1993
Applicant:
Inventors:
Ali Shafiee, Westfield, NJ (US);
Byron H Arison, Watchung, NJ (US);
Shieh-Shung T Chen, Morganville, NJ (US);
Randall R Miller, Piscataway, NJ (US);
Ralph A Stearns, Park Ridge, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ; C12P / ;
U.S. Cl.
CPC ...
540456 ; 435119 ;
Abstract
Microbial transformation of a macrolide immunosuppressant by the microorganism Streptomyces sp., (Merck Culture Collection MA 6960) ATCC No. 55387 yields a compound of the structural formula (I): ##STR1## This compound is an immunosuppressant useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases, the prevention of rejection of foreign organ transplants and/or related afflictions, diseases and illnesses.