The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 1994
Filed:
Jul. 31, 1992
Applicant:
Inventors:
Assignee:
Fidia S.p.A., Abano Terme, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12P / ; C07H / ;
U.S. Cl.
CPC ...
536 53 ; 435 84 ; 435101 ; 536 55 ; 536 551 ; 536 553 ;
Abstract
Novel ganglioside derivatives comprised of a basic natural or semisynthetic ganglioside, in which the carboxyl group in the sialic part of the natural or semisynthetic ganglioside is converted into a carboxylamide with an aliphatic amino acid with a carboxylic or sulfonic acid function, and salts thereof are prepared. The semisynthetic ganglioside components can be chosen from the group consisting of N-acyl-N-lyso-gangliosides, N'-acyl-N'-lyso-gangliosides and N,N'-diacyl-N,N'-di-lyso-gangliosides, wherein 'acyl' designates a moiety of an optionally substituted aliphatic acid. The ganglioside derivatives can be used in pharmaceutical preparations to be used in nervous system pathologies.