The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 1994

Filed:

Feb. 06, 1992
Applicant:
Inventors:

Yoshitaka Ohishi, Kyoto, JP;

Makoto Tamura, Kyoto, JP;

Mitsuo Hayashida, Kyoto, JP;

Satoru Ikegami, Kyoto, JP;

Yoshiyuki Hiyama, Kyoto, JP;

Takao Awa, Kyoto, JP;

Kiyonoshin Ichikawa, Kyoto, JP;

Kiyoshi Nomiyama, Kyoto, JP;

Keigo Hanada, Kyoto, JP;

Mitsuo Mimura, Kyoto, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F / ; A61K / ;
U.S. Cl.
CPC ...
514 89 ; 514 91 ; 514278 ; 546 16 ; 546 32 ; 548407 ; 548513 ; 548514 ;
Abstract

A bisphosphonic acid derivative of the formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein A is ##STR2## each of R.sup.3 and R.sup.4, which may be the same or different, is (i) a hydrogen atom, (ii) a C.sub.1-6 alkyl group, a C.sub.2-6 alkenyl group, a C.sub.2-6 alkynyl group, a C.sub.1-6 alkyl-carbonyl group, a C.sub.2-6 alkenyl-carbonyl group, a C.sub.2-6 alkynyl-carbonyl group R.sup.5 and R.sup.6, which may be the same or different, is a hydrogen atom, a hydroxyl group, a halogen atom, a cyano group, a carbamoyl group, an aralkyl group, a substituted or unsubstituted phenyl group, a substituted or unsubstituted amino group, a C.sub.1-6 alkyl group, a C.sub.2-6 alkenyl group, a C.sub.2-6 alkynyl group;


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