The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 1994
Filed:
Dec. 12, 1991
Applicant:
Inventors:
Thierry Boon, Brussels, BE;
Pierre van der Bruggen, Brussels, BE;
Benoit Van den Eynde, Brussels, BE;
Aline Van Pel, Brussels, BE;
Etienne De Plaen, Brussels, BE;
Christophe Lurquin, Brussels, BE;
Patrick Chomez, Brussels, BE;
Catia Traversari, Milan, IT;
Assignee:
Ludwig Institute for Cancer Research, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ; C12N / ; C12N / ; C12N / ; C12N / ; C12N / ; C12N / ; C07K / ; C07H / ;
U.S. Cl.
CPC ...
4352402 ; 435 691 ; 435 693 ; 4351723 ; 4353201 ; 4352351 ; 4352523 ; 536 235 ; 530350 ; 935-9 ; 935 32 ; 935 34 ; 935 57 ; 935 62 ; 935 70 ; 935 71 ;
Abstract
The invention relates to an isolated DNA sequence which codes for an antigen expressed by tumor cells which is recognized by cytotoxic T cells, leading to lysis of the tumor which expresses it. Also described are cells transfected by the DNA sequence, and various therapeutic and diagnostic uses arising out of the properties of the DNA and the antigen for which it codes.