The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 1994

Filed:

May. 04, 1992
Applicant:
Inventors:

Xavier Emonds-Alt, Combaillaux, FR;

Patrick Gueule, Teyrand, FR;

Vincenzo Proietto, Saint Georges d'Orques, FR;

Pierre Goulaouic, deceased, late of Montpellier, FR;

by Marie Bousquet, heir, Bourg la Reine, FR;

by Catherine Goulaouic, heir, Gif sur Yvette, FR;

Assignee:

Elf Sanofi, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514316 ; 514212 ; 5142355 ; 5142358 ; 514252 ; 514255 ; 514256 ; 514318 ; 514326 ; 514327 ; 514330 ; 514331 ; 540524 ; 540597 ; 540598 ; 544121 ; 544122 ; 544129 ; 544333 ; 544357 ; 544359 ; 544360 ; 544365 ; 544372 ; 546186 ; 546187 ; 546188 ; 546189 ; 546190 ; 546191 ; 546208 ;
Abstract

The invention relates to polycyclic amine compounds of formula (I) ##STR1## where Y. m. Ar', n, p, Q, T, q and Z are defined herein. The invention also relates to methods of making the compounds of formula (I) and pharmaceutical compositions which contain the compounds of formula (I). The inventive compounds are useful as neurokinin receptor antagonists, and are useful for the treatment of any substance P-dependent and neurokinin-dependent pathological condition.


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