The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 1994

Filed:

Oct. 30, 1992
Applicant:
Inventors:

Richard C Sutton, Rochester, NY (US);

Marsha B Oenick, Rochester, NY (US);

Assignee:

Eastman Kodak Company, Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; G01N / ; C08L / ; C08F / ;
U.S. Cl.
CPC ...
435-5 ; 435-6 ; 435-75 ; 435-792 ; 435-794 ; 435-795 ; 435962 ; 435969 ; 435970 ; 435974 ; 435975 ; 436518 ; 436523 ; 436531 ; 524817 ; 524825 ; 526286 ; 526293 ; 526320 ; 526346 ; 935 77 ; 935 78 ;
Abstract

Biologically active reagents are prepared from particles of copolymers having polyoxyalkylene side chains, each of which side chains has a molecular weight of at least about 88. The reagents are prepared by covalently attaching biologically active substances, for example antibodies, to the particles, directly or indirectly through reactive groups on the particle surface. These reagents are used to advantage in analytical elements and methods for the detection of specific binding ligands (such as immunological species) and immunoassays, and in purification methods as affinity chromatography reagents. Adsorption of undesirable proteins on the particles of the reagents was considerably reduced because of the specific composition of the particles.


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