The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 1994

Filed:

Mar. 24, 1993
Applicant:
Inventors:

Ulrich Seipp, Aachen, DE;

Werner Vollenberg, Stolberg, DE;

Werner Englberger, Stolberg, DE;

Cornelia Geist, Aachen, DE;

Michael Haurand, Stolberg, DE;

Assignee:

Gruenenthal GmbH, Aachen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
560254 ; 560221 ; 560223 ; 560225 ; 560250 ; 560251 ; 560255 ; 549 29 ; 549 74 ; 549 75 ; 549 76 ; 549 77 ; 546339 ; 546340 ; 546346 ; 574438 ; 574311 ; 574337 ; 574443 ;
Abstract

Oxyalkyne compounds corresponding to the formula I ##STR1## in which the substituent Y in the meta- or para-position is R.sup.1 represents CH.sub.3 or NH.sub.2, R.sup.2 represents H or CH.sub.3, R.sup.3 represents H, C.sub.1-3 -alkyl or COCH.sub.3, and Ar represents an aromatic residue selected from the group ##STR2## with the proviso that the substituents R.sup.4, R.sup.5 and R.sup.6 are the same or different and each substituent represents H, F, Cl, Br, C.sub.1-6 -alkyl, CF.sub.3 or C.sub.1-6 -alkoxy, and R.sup.7 represents H, F, Cl, Br, C.sub.1-3 -alkyl or CF.sub.3, in the form of their racemates or mixtures of diastereoisomers or in optically active form, which are suitable active ingredients in pharmaceutical compositions.


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