The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 1994
Filed:
May. 22, 1991
Yuh-ichiro Ichikawa, Tokyo, JP;
Hiroshi Akaba, Tokyo, JP;
Yuka Sugawara, Kashiwa, JP;
Hideo Sugimura, Tokyo, JP;
Kazuhisa Narita, Ageo, JP;
Akira Shiozawa, Omiya, JP;
Kouwa Yamashita, Urawa, JP;
Sayuri Kato, Urawa, JP;
Yukihiro Nishiyama, Aichi, JP;
Kenichi Matsubara, Suita, JP;
Takemitsu Nagahata, Toyonaka, JP;
Nippon Kayaku Kabushiki Kaisha, Tokyo, JP;
Abstract
This invention relates to cyclobutane derivatives represented by the following general formula (1) and physiologically acceptable salts thereof: ##STR1## wherein B represents a nucleic acid base derivative, R.sup.1 and R.sup.2 independently represent hydrogen atom, dialkylaminoacyl group, 1,4-dihydro-1-methylnicotinoyl group or substituted phosphoric acid group, provided that either one of R.sup.1 and R.sup.2 is a group other than hydrogen atom. The compounds of this invention exhibit a high oral absorbability and are metabolized in vivo into the compounds of formula (1a). Accordingly, the compounds of this invention are expectedly useful as antiviral agent.