The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 1994
Filed:
Feb. 28, 1991
Eliane Sobczak, Paris, FR;
Yves Malpiece, deceased, late of Amiens, FR;
Marie-Louise Michel, Paris, FR;
Pierre Tiollais, Paris, FR;
Rolf E Streeck, Paris, FR;
Institut Pasteur, Paris, FR;
Institut National De La Sante Et De La Rocherche Medicale, Paris, FR;
Centre National De La Recherche Scientifique, Paris, FR;
Abstract
The invention concerns a composition useful for the manufacture of vaccines containing particles having the immunogenic properties characteristic of the antigen HBsAg, these particles being more particularly characterized by the fact that the said particles equally contain a receptor for polymerized human albumin. They are obtained by transformation of human or animal cells by a vector containing a DNA sequence coding for the S and pre-S regions of a genome of viral hepatitis B, this DNA sequence being placed under the direct control of a promoter permitting the effective transcription of the said sequence in the human or animal cells transformable by the said vector.