The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 1994
Filed:
Feb. 25, 1993
Applicant:
Inventors:
Jens K Perregaard, Jaegerspris, DK;
Kim Andersen, Copenhagen, DK;
Klaus P Boegesoe, Lyngby, DK;
Henrik Pedersen, Broenshoej, DK;
Assignee:
H. Lundbeck A/S, Copenhagen-Valby, DK;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
514323 ; 514339 ; 546201 ; 546273 ;
Abstract
Specific 2- and 2,5-substituted indoles or 2,3-dihydroindole compounds of the following formula ##STR1## wherein, R is formula 1a ##STR2## and X, X', Ar, R.sup.1, n, U, Z, V and W are defined in the specification are provided, having long lasting serotonin activity with specific binding to 5-HT.sub.2 receptors of the central nervous system. These compounds are suitable for therapeutic treatment of CNS disorders, such as anxiety, depression, sleep disturbances, migraine, negative symptoms of schizophrenia, and Parkinson's disease.