The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 1994
Filed:
Jul. 29, 1993
Applicant:
Inventors:
Peter Crause, Offenbach, DE;
Paul Habermann, Eppstein am Taunus, DE;
Dominique Tripier, Eppstein am Taunus, DE;
Wolfgang Ulmer, Eppstein am Taunus, DE;
Gerhard Schmid, Munich, DE;
Assignee:
Hoechst Aktiengesellschaft, Frankfurt am Main, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
4353201 ; 435 691 ; 4351723 ; 4352523 ; 43525233 ; 43525421 ; 536 235 ; 935-9 ; 935 10 ; 935 28 ; 935 29 ; 935 56 ; 935 69 ; 935 73 ;
Abstract
Novel synthetic isohirudins with improved stability The invention relates to novel synthetic isohirudins which have improved stability owing to exchange in the region of the Asp-Gly motif. This results, on the one hand, in an increase in the yield during workup and, on the other hand, in making possible pharmaceutical formulation as directly injectable solution ready for use.