The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 1994
Filed:
May. 03, 1993
Nobuyoshi Hayashi, Kawanishi, JP;
Tohru Sugawara, Osaka, JP;
Takeda Chemical Industries, Ltd., Osaka, JP;
Abstract
an automated synthesizing apparatus which comprises a raw material, reagent and solvent supply unit, a reaction unit, a purification unit provided with HPLC and CPC, and a freeze-drying unit for freeze-drying a purified product supplied from the purification unit. The raw material, reagent and solvent supply unit includes a plurality of reservoirs for containing raw material, reagents and solvents; volumetric tubes and gas-liquid boundary sensors for the quantification of the raw material, reagents and solvents from the reservoirs; flow-lines for supplying the raw material, reagent and solvent from the reservoirs towards subsequent steps; and solenoid valve assemblies disposed on the respective flow-lines for selectively closing and opening such respective flow-lines. The reaction unit includes a reaction flask device adapted to receive the raw material from the raw material, reagent and solvent supply unit; a separation funnel for extracting or washing a product which is transferred from the reaction flask device; a pH adjusting flask for adjusting acidity or basicity of the reaction liquid from the separation funnel; a plurality of reagent reservoirs disposed for adding a predetermined quantity of reagent to the reaction flask device, volumetric tubes and gas-liquid boundary sensors. All of the units, the sensors and the solenoid valve assemblies of each of the units are so connected with a computer that the sequence of operation thereof can be controlled thereby.