The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 1994
Filed:
May. 12, 1993
Applicant:
Inventors:
Semiramis Ayral-Kaloustian, Tarrytown, NY (US);
Steven R Schow, Washingtonville, NY (US);
Mila T Du, Suffern, NY (US);
James J Gibbons, Jr, Westwood, NJ (US);
Assignee:
American Cyanamid Company, Wayne, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ;
U.S. Cl.
CPC ...
514478 ; 514 19 ; 514484 ; 514485 ; 514488 ; 514489 ; 514566 ; 544 584 ; 544168 ; 544224 ; 544237 ; 544335 ; 544355 ; 544383 ; 544390 ; 544406 ; 546146 ; 546147 ; 546255 ; 546262 ; 546496 ; 562439 ; 562560 ; 564 47 ; 564 57 ; 564 59 ; 548127 ; 548136 ; 548200 ; 548214 ; 548236 ; 548248 ; 548253 ; 5483335 ; 5483741 ; 548495 ; 548530 ; 549 72 ; 549365 ; 549366 ; 549487 ; 560 25 ; 560 28 ; 560 29 ; 560 32 ; 560 33 ; 560 34 ; 560115 ; 560158 ; 560159 ;
Abstract
The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Compounds in the invention or pharmaceutical compositions employing these compounds may be useful in the treatment of cancer, AIDS, aplastic anemia, myelodysplastic syndrome, and infectious diseases, and in the enhancement of immune response.