The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 1994
Filed:
Jul. 17, 1992
Applicant:
Inventors:
Wallace T Ashton, Clark, NJ (US);
Linda L Chang, Wayne, NJ (US);
William J Greenlee, Teaneck, NJ (US);
Steven M Hutchins, Iselin, NJ (US);
Ralph A Rivero, Tinton Falls, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ; A61K / ; A61K / ; A61K / ; C07C / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
5142275 ; 5142305 ; 5142348 ; 514297 ; 514312 ; 514313 ; 514346 ; 514349 ; 514381 ; 514394 ; 514418 ; 514419 ; 514450 ; 514471 ; 514596 ; 514597 ; 514598 ; 544 52 ; 544105 ; 544354 ; 544355 ; 544356 ; 549401 ; 549483 ; 549484 ; 549487 ; 546102 ; 546103 ; 546104 ; 546105 ; 546106 ; 546153 ; 546159 ; 546163 ; 546168 ; 546169 ; 546292 ; 548251 ; 5483064 ; 5483074 ; 5483615 ; 5483621 ; 548483 ; 560 27 ; 564 48 ; 564 49 ; 564 50 ; 564 51 ; 564 52 ;
Abstract
Carbamoyl and oxycarbonyl derivatives of biphenylmethylamines of structure I are angiotensin-II antagonists with balanced AT.sub.1 and AT.sub.2 activity useful in the treatment of hypertension and related disorders and ocular hypertension. ##STR1## where X is --O-- or --N(R.sup.7)--.