The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 1994

Filed:

Aug. 12, 1992
Applicant:
Inventor:

Richard S Bockman, Sag Harbor, NY (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514573 ; 514549 ;
Abstract

In this invention methods are described by which prostaglandins of the E.sub.1 class and compounds that mimic or induce cyclic adenosine monophosphate are used to block collagenase gene expression by cells responsible for connective and support tissue breakdown. The consequence of using pharmaceutically acceptable preparations of prostaglandin E.sub.1, analogs of prostaglandin E.sub.1 or cyclic adenosine monophosphate agonists or inducers of cyclic adenosine monophosphate is to preserve and protect connective and support tissues. These methods provide new treatment modalities useful in protecting humans and animals against connective and support tissue degradation that occurs in aging, osteoporosis and osteoarthritis.


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