The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 1994
Filed:
Mar. 26, 1992
Steven R Freebersyser, St. Louis County, MO (US);
Mallinckrodt Specialty Chemicals Company, Chesterfield, MO (US);
Abstract
A product and process for preparing a pharmaceutical composition for forming tablets, the composition containing pamabrom and pyrilamine maleate. In preferred embodiments, the composition also contains acetaminophen. A fluid bed granulator is charged with a first material containing pamabrom or pyrilamine maleate, and a first liquid containing pregelatinized starch is sprayed onto the first material so as to form a barrier coat. The barrier coated material is dried and then further coated with a second liquid containing only one of pamabrom and pyrilamine maleate, whichever was not present in the first material charged to the fluid bed granulator. The further coated material is then dried to a moisture content of from about 0.5% to less than about 2% by weight, so as to form particles in which the pamabrom and pyrilamine maleate are separated by the pregelatinized starch barrier.