The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 1994

Filed:

Feb. 26, 1993
Applicant:
Inventors:

Koichi Kojima, Tokyo, JP;

Hitoshi Kurata, Tokyo, JP;

Hiroyoshi Horikoshi, Tokyo, JP;

Takakazu Hamada, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07J / ;
U.S. Cl.
CPC ...
514284 ; 514253 ; 514256 ; 544238 ; 544295 ; 544296 ; 544333 ; 544335 ; 544336 ; 544405 ; 546 77 ;
Abstract

Compounds of formula (I): ##STR1## (in which: R.sup.1 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or a heterocyclic-substituted alkyl group; R.sup.2 is an aryl-substituted alkyl group, a heterocyclic-substituted alkyl group or a diarylamino group; R.sup.3 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or an alkenyl group having from 3 to 6 carbon atoms; and each of the bonds represented by .alpha.-.beta. and .gamma.-.delta. is a carbon-carbon single bond or a carbon-carbon double bond;) and pharmaceutically acceptable salts and esters thereof are useful for the treatment and prophylaxis of prostatic hypertrophy. We also provide processes for their preparation.


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