The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 1994
Filed:
Nov. 18, 1991
Carlos A Rabito, Medford, MA (US);
Richard H Moore, Concord, MA (US);
Massachusetts General Hospital, Boston, MA (US);
Abstract
Accurate and continuous monitoring of clearance function is obtained by determining the depletion of a labelled substance from the extracellular body fluid using an external monitor which detects label from within a defined tissue volume. The detector of the external monitor is contained within a collimator which functions to both exclude external influences and to functionally isolate the volume of extracellular fluid to be monitored. Also, a method for determining and expressing a clearance function in a subject includes steps of allowing a time sufficient to permit establishment of equilibrium of a detectable substance in the extracellular space in the subject, obtaining first and second measures, at first and second times, of the detectable substance in the extracellular fluid within a defined tissue volume in the subject, and determining the slope of the measures over the time interval.