The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 1994

Filed:

Dec. 08, 1992
Applicant:
Inventors:

Kuo-Hsiung Lee, Chapel Hill, NC (US);

Yung-Chi Cheng, Woodbridge, CT (US);

Yi-Lin Zhang, Chapel Hill, NC (US);

Assignees:

The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);

Yale University, New Haven, CT (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
5142325 ; 514338 ; 514422 ; 514424 ; 514463 ; 514468 ; 544148 ; 544152 ; 546197 ; 546214 ; 548526 ; 549298 ;
Abstract

Novel podophyllotoxin compounds and their use in treating tumors are disclosed. In one embodiment, the compounds have the general formula: ##STR1## wherein NH-R is a selected from the from the group consisting of: ##STR2##


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