The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 1994

Filed:

Sep. 25, 1991
Applicant:
Inventors:

Michael E Hrinda, Gwynedd Valley, PA (US);

Rose D'Alisa, Warrington, PA (US);

George C Tarr, Jeffersonville, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
435238 ; 435236 ; 514 21 ; 424530 ; 424 943 ; 530381 ; 530384 ; 530380 ;
Abstract

The present invention provides a fail-safe combination of chemical and physical means for rendering a blood product which comprises a labile blood protein free of viruses without incurring protein denaturation. The blood product is contacted with an effective amount of a selected chemical disinfectant, preferably, sodium thiocyanate in combination with a physical process, preferably, ultrafiltration. The blood product may be plasma, serum, plasma concentrate, cryoprecipitate, cryosupernatant, plasma fractionation precipitate or plasma fractionation supernatant containing viruses such as hepatitis or human immunodeficiency virus.


Find Patent Forward Citations

Loading…