The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 1994
Filed:
Nov. 12, 1992
Applicant:
Inventors:
Susumu Nakagawa, Okazaki, JP;
Akira Asai, Okazaki, JP;
Satoru Kuroyanagi, Okazaki, JP;
Makoto Ishihara, Okazaki, JP;
Yoshiharu Tanaka, Okazaki, JP;
Assignee:
Banyu Pharmaceutical Co., Ltd., Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07D / ;
U.S. Cl.
CPC ...
549 49 ; 549 55 ; 549 58 ; 549 59 ; 549 60 ; 549 61 ; 549 64 ; 549 65 ; 549 74 ; 549 75 ; 556483 ; 558257 ; 560 34 ; 560 38 ; 560 61 ; 560 62 ; 560 65 ;
Abstract
A process for producing an enyne derivative, and intermediate, which is useful for preparing compounds showing strong inhibiting activities against squalane epoxidase of Eumycetes and strong anti-cholesterol activities. The process comprises reacting a compound of the formula: ##STR1## wherein W is a halogen atom, with an acetylene derivative, in the presence of a palladium catalyst, to obtain a compound of the formula: ##STR2## and, if necessary, N-alkylating this compound.