The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 1994

Filed:

Jun. 25, 1992
Applicant:
Inventors:

Takakazu Endo, Kanagawa, JP;

Koji Tamura, Kanagawa, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ;
U.S. Cl.
CPC ...
435280 ; 435146 ; 435822 ;
Abstract

A process for treating R,S-mandelonitrile or a derivative thereof or a mixture of benzaldehyde or a derivative thereof, and; hydrogen cyanide, with a microorganism belonging to the genus Rhodococcus sp. HT29-7 (FERM BP-3857) in an almost neutral or basic aqueous medium to thereby directly produce a predominant amount of R(-)-mandelic acid or a derivative thereof, whereby the racemic R,S-mandelonitrile or a derivative thereof or benzaldehyde or a derivative thereof and hydrogen cyanide can be directly converted into R(-)-mandelic acid or a derivative thereof at a ratio of about 80 to 100% and at an optical purity of almost 100%.sub.ee without performing any optical resolution.


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