The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 1994
Filed:
Apr. 05, 1991
Applicant:
Inventors:
Michiko Yamayoshi, Toyonaka, JP;
Hitoshi Kawashima, Osaka, JP;
Junichi Yamagishi, Nara, JP;
Hirotada Kotani, Sakai, JP;
Ryuji Furuta, Otsu, JP;
Toshikazu Fukui, Settsu, JP;
Assignee:
Dainippon Pharmaceutical Co., Ltd., Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ;
U.S. Cl.
CPC ...
530351 ; 930141 ; 424 852 ; 435 6952 ; 435 695 ;
Abstract
Novel polypeptides having a modified amino acid sequence of human interleukin 1.alpha. polypeptides in which a certain amino acid residue(s) in said amino acid sequence is(are) exchanged for other amino acid residue(s). Said polypeptides having no capacity of induction of production of prostaglandin E.sub.2 while maintaining other biological activities of human interleukin 1 such as activation of lymphocyte and being expected to be useful as a medicament.