The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 1994
Filed:
Aug. 03, 1992
Applicant:
Inventors:
Thomas Quertermous, Cambridge, MA (US);
Mu-En Lee, Boston, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
4351723 ; 4352402 ; 4353201 ; 536241 ; 935-6 ; 935 33 ; 935 34 ; 935 36 ;
Abstract
Methods and compositions for cell-specific expression of genes are provided. The invention utilizes the endothelin-1 promoter and promoter elements to direct expression of heterologous genes in endothelial cells. The promoters and elements are useful for directing cell-specific expression of therapies for vascular and cardiovascular diseases.