The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 1994
Filed:
Aug. 05, 1992
Applicant:
Inventors:
John E Airey, King of Prussia, PA (US);
Matthew R Powers, Barto, PA (US);
Walter Rodriguez, Douglasville, PA (US);
Raymond D Youssefyeh, Princeton Junction,, NJ (US);
Assignee:
Rhone-Poulenc Rorer Pharmaceuticals Inc., Collegeville, PA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514305 ; 5142242 ; 5142305 ; 514299 ; 514304 ; 514320 ; 544 47 ; 544105 ; 546112 ; 546126 ; 546133 ; 546196 ; 546354 ; 546355 ; 546386 ;
Abstract
Novel compounds which are 2,6-methano-2H-1-benzoxocincarboxamides having 5-HT.sub.3 -antagonist properties including unique CNS, antiemetic and gastric prokinetic activities and which are void of any significant D.sub.2 receptor binding affinity, therapeutic compositions and methods of treatment of disorders which result from 5-HT.sub.3 activity using said compounds. Processes for their preparation and the preparation of their intermediates are also disclosed.