The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 1994

Filed:

Nov. 21, 1990
Applicant:
Inventors:

Stephen L Buchwald, Somerville, MA (US);

Kristina A Kreutzer, Cambridge, MA (US);

Esther Spaltenstein, Raleigh, NC (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07P / ; C07P / ; C07C / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
548577 ; 548400 ; 548578 ; 562400 ; 568814 ; 568831 ;
Abstract

A process is provided whereby organic carbonyl substrates, including esters, ketones and amides, are reduced in a reaction with a silane reducing reagent and a catalyst. Effective catalysts broadly include those which consist of a group 4, 5 or 6 metal which either: a) is in less than its maximum oxidation state or is capable of being converted to a complex in less than its maximum oxidation state; and/or is a group 4, 5 or 6 metal hydride. Exemplary catalysts include titanium-containing catalysts such as (bis trimethylphosphine) titanocene, trimethyl phosphine adduct of a (hydrido) silyl complex of titanocene, titanocene dichloride and titanocene monochloride.


Find Patent Forward Citations

Buchwald, Stephen. (1994). Catalytic reduction of organic carbonyls (U.S. Patent No. 5286878). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5286878

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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